Rapid Antigen Test as Screening Strategy at Points of Entry

COVID-19 Speedy Antigen Take a look at as Screening Technique at Factors of Entry: Expertise in Lazio Area, Central Italy, August-October 2020

COVID-19 pandemic is a dramatic well being, social and financial international problem. There may be pressing want to maximise testing capability. Speedy Antigen Exams (RAT) symbolize good candidates for point-of-care and mass surveillance testing to quickly determine SARS-CoV-2-infected folks, counterbalancing decrease sensitivity vs. gold normal molecular assessments with quick outcomes and potential recurrent testing. We describe the outcomes obtained with the testing algorithm applied at factors of entry (airports and ports) within the Lazio Area (Italy), utilizing the STANDARD F COVID-19 Antigen Fluorescence ImmunoAssay (FIA), adopted by molecular affirmation of FIA-positive samples.

From mid-August to mid-October 2020, 73,643 RAT had been reported to the Regional Surveillance Data System for vacationers at factors of entry in Lazio Area. Of those, 1176 (1.6%) had been FIA-positive, and the proportion of RT-PCR-confirmed samples was 40.5%. Our information present that the chance of affirmation was straight dependent from the semi-quantitative FIA outcomes. As well as, the molecularly confirmed samples had been these with excessive ranges of virus and that had been truly harboring infectious virus. These outcomes assist public well being methods based mostly on early mass screening campaigns by RAT in settings the place molecular testing isn’t possible or simply accessible, resembling factors of entry. This strategy would contribute to promptly controlling viral unfold by journey, which is now of specific concern as a result of unfold of SARS-CoV-2 variants.

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Quinolones (QNs) Rapid Test Kit

abx092067-40tests 40 tests
EUR 477.6

Clenbuterol (CLE) Rapid Test Kit

abx092058-50tests 50 tests
EUR 292.8

Ractopamine (RAC) Rapid Test Kit

abx092059-50tests 50 tests
EUR 292.8

Tetracycline (TCs) Rapid Test Kit

abx092063-50tests 50 tests
EUR 477.6

Sulfonamides (Sas) Rapid Test Kit

abx092064-40tests 40 tests
EUR 477.6

Brucella Antibody Rapid Test Kit

abx092069-40tests 40 tests
EUR 427.2

Ciprofloxacin (CPFX) Rapid Test Kit

abx092066-50tests 50 tests
EUR 477.6

HBeAg hepatitis B E antigen ELISA test

79 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HBeAg hepatitis B E antigen

NOVATest IgG/IgM Antibody Rapid Test Kit (NOVA Test)

UNCOV-40 40 Tests
EUR 115

Procalcitonin rapid test (Colloidal Gold)

abx095264-80Units 80 Units
EUR 1144.8

Cow Brucella Antibody Rapid Test Kit

abx092071-40tests 40 tests
EUR 427.2

Goat Brucella Antibody Rapid Test Kit

abx092070-40tests 40 tests
EUR 427.2

NOVATest Antigen Rapid Test Kit (For Single Use) (NOVA Test)

nCov-500-01 1T
EUR 162

Chlamydia Rapid Test Device (Swab/Urine)

173-8537306 20 Tests/Kit
EUR 300

Pig Parvovirus Antibody Rapid Test Kit

abx092074-50tests 50 tests
EUR 385.2

Aflatoxin Rapid Test Kit (Colloidal gold)

abx092054-50tests 50 tests
EUR 477.6

Dynamiker Monkeypox Virus Ag Rapid Test

DNK-2114-1 20 tests
EUR 702
Description: The product is a lateral flow chromatographic immunoassay for the qualitative detection of monkeypox virus antigen in human whole blood, serum, plasma or rash exuudate. The kit is intended for professional use only.

Salbutamol Rapid Test Kit (Colloidal gold)

abx092043-50tests 50 tests
EUR 410.4

Quinolones Rapid Test Kit (Colloidal gold)

abx092046-50tests 50 tests
EUR 644.4

COVID-19 IgG/IgM Rapid Test Kit

UNCOV-20 20T/kit
EUR 186
Description: COVID-19 IgG/IgM Rapid Test (Serum/Plasma/Whole Blood) is a qualitative membrane-based immunoassay for the detection of COVID-19 antibodies in serum, plasma, or whole blood. This test consists of two test lines, an IgG line and an IgM line, which is pre-coated with two mouse anti-human monoclonal antibodies separately. During testing, the sample reacts with COVID-19 antigen-coated on conjugated pad. As the complex continues to travel up the strip, the anti-COVID-19 IgM antibodies are bound on the IgM line, and the anti-COVID-19 IgG antibodies are bound on the IgG line. The control(C)line appears when sample has flowed through the strip. The presence of anti-COVID-19 IgM and/or IgG will be indicated by a visible test line in the IgM and IgG region. To serve as a procedural control, the control line should always appear if the test procedure is performed properly and the reagents are working as intended.

Clenbuterol Rapid Test Kit (Colloidal gold)

abx092040-50tests 50 tests
EUR 326.4

Ractopamine Rapid Test Kit (Colloidal gold)

abx092042-50tests 50 tests
EUR 360

Zearalenone Rapid Test Kit (Colloidal gold)

abx092051-50tests 50 tests
EUR 493.2

Zearalenone Rapid Test Kit (Colloidal gold)

abx092056-50tests 50 tests
EUR 510

Sulfonamides Rapid Test Kit (Colloidal gold)

abx092047-50tests 50 tests
EUR 661.2

Tetracycline Rapid Test Kit (Colloidal gold)

abx092048-50tests 50 tests
EUR 560.4

Fetal Fibronectin rapid test (Colloidal Gold)

abx095261-80Units 80 Units
EUR 1863.6

Deoxynivalenol Rapid Test Kit (Colloidal gold)

abx092052-50tests 50 tests
EUR 560.4

Deoxynivalenol Rapid Test Kit (Colloidal gold)

abx092053-50tests 50 tests
EUR 560.4

SARS-CoV-2 Antigen Rapid Test Kit

CoV2Ag-1 1T
EUR 9.6
Description: This kit adopts the sandwich method and the technical principle of colloidal gold immunochromatography to qualitative determine the SARS-CoV-2 antigen. During the test, the sample is dropped into the sample well, and chromatography is performed under the capillary effect. The SARS-CoV-2 antigen in the sample combined with the colloidal goldlabeled SARS-CoV-2 monoclonal antibody I, and then spread to the test area. It is captured by another coated antibody (SARS-CoV-2 monoclonal antibody II), to form a complex and gather in the test area (T line). The quality control area is coated with the goat antimouse antibody, and the colloidal gold-labeled antibody is captured to form a complex and aggregate in the quality control area (C line). If the C line does not show color, it indicates that the result is invalid, and this sample needs to be tested again.

SARS-CoV-2 Antigen Rapid Test Kit

CoV2Ag-25 25T/kit
EUR 42
Description: This product is used for in vitro qualitative detection of SARS-CoV-2 antigen in human oropharyngeal swabs, nasal swabs and nasopharyngeal swabs. It is helpful as an aid in the screening of early mild, asymptomatic, or acute patients for identification of SARS-CoV-2 infection.

Chloramphenicol Rapid Test Kit (Colloidal gold)

abx092045-50tests 50 tests
EUR 427.2

Rat ABCA1(ATP Binding Cassette Transporter A1) ELISA Kit

ER1451 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.094 ng/ml

Human Echovirus (ECHO) IgM Rapid Test Kit

abx092093-20tests 20 tests
EUR 326.4

Human Toxoplasma (TOX) IgG Rapid Test Kit

abx092098-20tests 20 tests
EUR 260.4

Rat ABCA13(ATP Binding Cassette Transporter A13) ELISA Kit

ER1861 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 28.1pg/ml

Mouse ABCG1(ATP Binding Cassette Transporter G1) ELISA Kit

EM0265 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

Human ABCC5(ATP Binding Cassette Transporter C5) ELISA Kit

EH0475 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml

Human ABCG1(ATP Binding Cassette Transporter G1) ELISA Kit

EH0476 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human ABCA13(ATP Binding Cassette Transporter A13) ELISA Kit

EH4870 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml

Aflatoxin B1 Rapid Test Kit (Colloidal gold)

abx092055-50tests 50 tests
EUR 477.6

Aflatoxin B1 Rapid Test Kit (Colloidal gold)

abx092050-50tests 50 tests
EUR 444

TruStrip RDT Testosterone Rapid Test cards, 10/pk

1880-RDT-10 1 pk Ask for price

Malachite Green Rapid Test Kit (Colloidal gold)

abx092041-10tests 10 tests
EUR 360

NOVATest Antigen Rapid Kit (NOVA Test)

nCov-500 20 Tests
EUR 162

Panbio™ COVID-19 IgG/IgM Rapid Test

ICO-T402 25 Tests/Kit
EUR 264

Panbio™ COVID-19 Ag Rapid Test Device

41FK10 25 Tests/Kit
EUR 115.2

Human Rubella Virus (RV) IgG Rapid Test Kit

abx092097-20tests 20 tests
EUR 260.4

Human Rabies Virus (HRV) IgG Rapid Test Kit

abx092100-20tests 20 tests
EUR 410.4

Recombinant human ATP-binding cassette sub-family A member 7

P2744 100ug Ask for price
Description: Recombinant protein for human ATP-binding cassette sub-family A member 7

Recombinant human ATP-binding cassette sub-family A member 12

P2922 100ug Ask for price
Description: Recombinant protein for human ATP-binding cassette sub-family A member 12

Recombinant human ATP-binding cassette sub-family A member 13

P2923 100ug Ask for price
Description: Recombinant protein for human ATP-binding cassette sub-family A member 13

Human Hantavirus (HV) IgM / IgG Rapid Test Kit

abx092094-20tests 20 tests
EUR 326.4

Human Hepatitis A Virus IgG Rapid Test Kit

abx092012-25tests 25 tests
EUR 510

Influenza Rapid Test Control Pack (3 X 1.5mL)

KZMC033 3 X 1.5mL
EUR 59

Rotavirus Rapid Test Control Pack (2 X 1.5mL)

KZMC036 2 X 1.5mL
EUR 59

Rat ABCG2(ATP-binding cassette sub-family G member 2) ELISA Kit

ER1862 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 46.875pg/ml

Human Enterovirus 71 (EV71) IgM Rapid Test Kit

abx092091-20tests 20 tests
EUR 410.4

Adenovirus Rapid Test Control Pack (2 X 1.5mL)

KZMC035 2 X 1.5mL
EUR 59

Phenylethanolamine A Rapid Test Kit (Colloidal gold)

abx092044-50tests 50 tests
EUR 560.4

Furaltadone Metabolite Rapid Test Kit (Colloidal gold)

abx092035-50tests 50 tests
EUR 644.4

Human ABCA7(ATP-binding cassette sub-family A member 7) ELISA Kit

EH1708 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Mouse Abca1(ATP-binding cassette sub-family A member 1) ELISA Kit

EM0552 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

Mouse Abca7(ATP-binding cassette sub-family A member 7) ELISA Kit

EM0635 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

Mouse AbCG3(ATP-binding cassette sub-family G member 3) ELISA Kit

EM0796 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml

Human ABCG2(ATP-binding cassette sub-family G member 2) ELISA Kit

EH1095 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human ABCB5(ATP-binding cassette sub-family B member 5) ELISA Kit

EH1172 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human ABCA1(ATP-binding cassette sub-family A member 1) ELISA Kit

EH1420 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Furazolidone Metabolite Rapid Test Kit (Colloidal gold)

abx092036-50tests 50 tests
EUR 644.4

Nitrofurazone Metabolite Rapid Test Kit (Colloidal gold)

abx092038-50tests 50 tests
EUR 644.4

Cattle and Goat Hydatid Antibody Rapid Test Kit

abx092072-40tests 40 tests
EUR 427.2

Human Helicobacter Pylori (HP) IgG Rapid Test Kit

abx092090-20tests 20 tests
EUR 276

Human Chlamydia Pneumoniae (CP) IgG Rapid Test Kit

abx092079-20tests 20 tests
EUR 309.6

Human Chlamydia Pneumoniae (CP) IgM Rapid Test Kit

abx092080-20tests 20 tests
EUR 309.6

TruStrip RDT Rat IgG Rapid Test cards, 10/pk

6420-RDT-10 1 Pk
EUR 205.2

TruStrip RDT Rat IgG Rapid Test cards, 25/pk

6420-RDT-25 1 Pk
EUR 351.6

TruStrip RDT Pig IgG Rapid Test cards, 10/pk

9020-RDT-10 1 Pk
EUR 205.2

TruStrip RDT Pig IgG Rapid Test cards, 25/pk

9020-RDT-25 1 Pk
EUR 351.6

Human Mycoplasma Pneumoniae (MP) IgG Rapid Test Kit

abx092081-20tests 20 tests
EUR 309.6

Human Mycoplasma Pneumoniae (MP) IgM Rapid Test Kit

abx092082-20tests 20 tests
EUR 309.6

TruStrip RDT Goat IgG Rapid Test cards, 10/pk

7520-RDT-10 1 Pk
EUR 205.2

TruStrip RDT Goat IgG Rapid Test cards, 25/pk

7520-RDT-25 1 Pk
EUR 351.6

SARS-CoV-2 Rapid Antigen Test Nasal

9901-NCOV-03G 25 Tests/Kit
EUR 112.8
Description: The SARS-CoV-2 Rapid Antigen Test is a lateral fl ow rapid chromatographic immunoassay for the qualitative detection of nucleocapsid antigen to SARS-CoV-2 present in human nasal samples. This test is intended for use as an aid in detection of SARS-CoV-2 infection in individuals suspected of COVID-19 with clinical symptoms onset within 5 days. Results are for the identification of SARS-CoV-2 nucleocapsid antigen. Antigen is generally detectable in human nasal swab samples during the acute phase of infection. Positive results indicate the presence of viral antigens, but clinical correlation with patient history and other diagnostic information is necessary to determine infection status. Positive results do not rule out bacterial infection or co- infection with other viruses. The agent detected may not be the definite cause of disease. Negative results should be treated as presumptive, and do not rule out SARS-CoV-2 infection and should not be used as the sole basis for treatment or patient management decisions, including infection control decisions. Negative results should be considered in the context of a patient’s recent exposures, history and the presence of clinical signs and symptoms consistent with COVID-19, and confirmed with a molecular assay, if necessary, for patient management. The SARS-CoV-2 Rapid Antigen Test is intended for use in laboratory or POC settings by healthcare professionals, or self-collection under the supervision of a healthcare worke

Cardiac Troponin I (cTnI) rapid test (Colloidal Gold)

abx095265-80Units 80 Units
EUR 1579.2

Avian Influenza H5N1 Virus Antibody Rapid Test Kit

abx092075-40tests 40 tests
EUR 477.6

TruStrip RDT Human IgG Rapid test cards, 10/pk

20007-1-RDT 1 Pk
EUR 205.2

TruStrip RDT Human IgG Rapid test cards, 25/pk

20007-1-RDT-25 1 Pk
EUR 351.6

TruStrip RDT Llama IgG Rapid test cards, 10/pk

20030-RDT-10 1 Pk
EUR 205.2

TruStrip RDT Llama IgG Rapid test cards, 25/pk

20030-RDT-25 1 Pk
EUR 351.6

TruStrip RDT Sheep IgG Rapid Test cards, 10/pk

7620-RDT-10 1 Pk
EUR 205.2

Antibody titers and fast antigen testing in aged sufferers with SARS-CoV-2 pneumonia vs. workers of ICU and “Covid-19” wards

 

Intention: Nearly all of sufferers hospitalized with COVID-19 are older people. Age and the comorbidities usually related to it normally go hand in hand with a much less favorable course of the illness. We had been within the antibody response on this specific affected person group in addition to within the outcomes of fast antigen testing.

Strategies: In 30 aged sufferers (>75 years), antibody titers (IgA and IgG) in opposition to COVID-19 had been measured, and fast antigen testing was decided about three weeks after the onset of signs of SARS-CoV-2 an infection. The outcomes had been in contrast with these of a “high-risk” group consisting of “Covid-19” ward common workers, in addition to with “low-risk” workers consisting of members of the intensive care unit (ICU). The antibody titer in opposition to SARS-CoV-2 was decided by ELISA (EUROIMMUN™, PerkinElmer, Inc. Firm); for fast antigen testing, we used the SARS-CoV-2 Speedy Antigen check (Roche®).

Outcomes: Our investigations show a sturdy antibody response within the majority of aged, comorbid sufferers about three weeks after the onset of an infection. At this timepoint, many of the outcomes of fast antigen testing had been unfavourable. Moreover, within the group of workers of our clinic (“Covid-19” ward vs. the ICU workers), the prevalence of antibodies was very low and antigen testing was unfavourable in the entire ICU group.

Conclusion: Though incessantly comorbid, aged sufferers are able to considerably rising antibodies in opposition to COVID-19 about three weeks after the onset of an infection. Because the viral load could be assumed to have been low at that time, fast antigen testing was unfavourable normally. Within the check group of workers of our clinic (“Covid-19” ward vs. the ICU workers), the info show that – given ample protecting measures – the chance of an infection isn’t increased in a “Covid-19” ward in comparison with different wards.

Diagnostic accuracy of two business SARS-CoV-2 antigen-detecting fast assessments on the level of care in community-based testing facilities

 

Targets: Decide the diagnostic accuracy of two antigen-detecting fast diagnostic assessments (Ag-RDT) for SARS-CoV-2 on the level of care and outline people’ traits offering finest efficiency.

Strategies: We carried out a potential, single-center, level of care validation of two Ag-RDT compared to RT-PCR on nasopharyngeal swabs.

Outcomes: Between October ninth and 23rd, 2020, 1064 individuals had been enrolled. The PanbioTM Covid-19 Ag Speedy Take a look at system (Abbott) was validated in 535 individuals, with 106 optimistic Ag-RDT outcomes out of 124 optimistic RT-PCR people, yielding a sensitivity of 85.5% (95% CI: 78.0-91.2). Specificity was 100.0% (95% CI: 99.1-100) in 411 RT-PCR unfavourable people. The Customary Q Ag-RDT (SD Biosensor, Roche) was validated in 529 individuals, with 170 optimistic Ag-RDT outcomes out of 191 optimistic RT-PCR people, yielding a sensitivity of 89.0% (95%CI: 83.7-93.1). One false optimistic consequence was obtained in 338 RT-PCR unfavourable people, yielding a specificity of 99.7% (95%CI: 98.4-100). For people presenting with fever 1-5 days submit symptom onset, mixed Ag-RDT sensitivity was above 95%. Decrease sensitivity of 88.2% was seen on the identical day of symptom improvement (day 0).

Conclusions: We offer an unbiased validation of two broadly obtainable business Ag-RDTs, each assembly WHO standards of ≥80% sensitivity and ≥97% specificity. Though much less delicate than RT-PCR, these assays may very well be useful because of their fast outcomes, ease of use, and independence from current laboratory constructions. Testing standards specializing in sufferers with typical signs of their early symptomatic interval onset might additional improve diagnostic worth.

 

Comparability of 5 SARS-CoV-2 fast antigen assessments in a hospital setting and efficiency of 1 antigen assay in routine observe. A useful gizmo to information isolation precautions?

 

Background: In a hospital setting, there’s a want for fast detection of SARS-CoV-2 to information isolation measures and focused admission.

Intention: First, we evaluated the diagnostic efficiency of 5 SARS-CoV-2 fast nucleocapsid protein antigen detection (RAD) assays (Biosynex, Biotical, Orient Gene, Panbio, SD Biosensor). Secondly, we described the efficiency and impression of the implementation of the SD Biosensor assay at our emergency division.

Strategies: Sensitivity and specificity of the 5 RAD assays had been analyzed on 100 respiratory samples: 60 real-time reverse-transcriptase-polymerase chain response (rRT-PCR) confirmed SARS-CoV-2 optimistic samples, 24 SARS-CoV-2 RNA unfavourable samples and 16 samples optimistic for different respiratory pathogens. We tailored the producer’s protocol, to validate the antigen assessments on transport media used for rRT-PCR in our routine observe. The SD Biosensor RAD assay was applied as screening technique for fast prognosis and focused admission.

Findings: Sensitivity of the included RAD assays ranged from 88.9% to 100% for samples with Ct <26, specificity from 46.2% to 100%. In the course of the implementation interval, 4195 RAD assessments had been carried out. As a result of fast RAD consequence, 157 sufferers had been transferred on to the COVID-19 cohort as a substitute of the common ward (n=47) or the non permanent COVID-19 ward (n=110).

Conclusion: The SD Biosensor, Biotical and Panbio SARS-CoV-2 antigen assessments had an appropriate general efficiency and appear to have the ability to detect many of the contagious sufferers. Within the context of excessive prevalence of SARS-CoV-2, RAD assessments can be utilized as a fast screening instrument, to information an infection prevention measures and help focused admission.

 

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