April 19, 2021

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3d rendering of X chromosomes in genetics research concept

The advent of genome-wide SNP typing and NGS genotyping methods heralds new insights and innovations for the fields of histocompatibility, immunogenetics and immunogenomics. However, the scope of the “big-data” generated using these technologies presents new challenges for their management, exchange, integration and application. The Informatics of Genomic Data component of the 17th Workshop has been established to assess and address these challenges, with the overall goal of identifying data-related “best-practices” and standards for maximizing the utility of these new methods. The leaders of this component are Steven J. Mack, Jill A. Hollenbach, Martin Maiers, and Paul J. Norman.

The Informatics of Genomic Data component includes the Informatics Core as well as a series of Informatics Projects. The Informatics Core is a central facility for the collection, storage, exchange and analysis of all workshop data and data-analysis results. Initial Quality Control (QC) evaluations, for the enrollment of experimental-data-generating laboratories, and periodic Quality Assurance (QA) evaluations will also be stored and scored in the Informatics Core.about:blankImageUpload an image file, pick one from your media library, or add one with a URL.UploadMedia LibraryInsert from URL

The web-portal for the Informatics Core can be found at http://workshop.17ihiw.org. Using this portal, investigators can register for the 17th Workshop, enroll members of their laboratories and research teams, enroll in components and projects, upload sample demographic data, pedigrees, typing results and typing meta-data, and apply for data access privileges. Raw NGS read data can be submitted to the Informatics Core via the exchange of physical hard drives, or via an SFTP portal that will be opened later this year.

Where possible, the Informatics Core will support centralized data-analyses for projects in in all workshop components; these functions will be activated over the course of 2016. While some analyses may be performed outside of the Informatics Core, the results of those analyses will be stored in the Informatics Core as well.