Description
Meticulously reviewed and updated for today’s medical students, Basic Immunology, 6th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology. This focused, easy-to-understand volume uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases—all designed to help students master this complex topic in the most efficient, effective manner possible.
Table of Contents
- Introduction to the Immune System
- Nomenclature, General Properties, and Components
- Innate Immunity
- The Early Defense Against Infections
- Antigen Capture and Presentation to Lymphocytes
- What Lymphocytes See
- Antigen Recognition in the Adaptive Immune System
- Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires
- T Cell–Mediated Immunity
- Activation of T Lymphocytes
- 6 Effector Mechanisms of T Cell–Mediated Immunity
- Functions of T Cells in Host Defense
- Humoral Immune Responses
- Activation of B Lymphocytes and Production of Antibodies
- Effector Mechanisms of Humoral Immunity
- Elimination of Extracellular Microbes and Toxins
- Immunological Tolerance and Autoimmunity
- Self-Nonself Discrimination in the Immune System and Its Failure
- Immune Responses Against Tumors and Transplants
- Immunity to Noninfectious Transformed and Foreign Cells
- Hypersensitivity
- Disorders Caused by Immune Responses
- Congenital and Acquired Immunodeficiencies
- Diseases Caused by Defective Immunity
- Selected Readings
- Appendix I Glossary
- Appendix II Cytokines
- Appendix III Principal Features of Selected CD Molecules
- APPENDIX IV Clinical Cases